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One of the main players here is the **PI3K/AKT/mTOR pathway**, which regulates cell growth, survival, and metabolism. In many TNBC cases, this pathway is overactive, driving uncontrolled cell proliferation. Another important player is the **Wnt signaling pathway**. This pathway is involved in cell development and cell fate. Aberrant activation of this pathway has been linked to TNBC. Another pathway that comes into play is the **p53 pathway**. As mentioned earlier, TP53 is often mutated or inactivated in TNBC. When this happens, the p53 pathway, which normally acts as a tumor suppressor, can't do its job properly, leading to cancer. These are not the only players, but they highlight the complexity and interconnectedness of cellular processes in TNBC.
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* **Exploring Important Social Issues:** *Grey's Anatomy* has a history of tackling social issues, and Season 16 was no exception. The show addressed topics such as mental health, healthcare inequality, and the challenges faced by working parents. By incorporating these issues into its storylines, *Grey's Anatomy* sparked conversations and raised awareness among its viewers.
